重组人白介素-16,Recombinant Human Interleukin 16 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C600452

重组人白介素-16

英文名	Recombinant Human Interleukin 16
别名	IL-16; IL16; LCF; NIL16; PRIL16; PRIL-16
相关类别	重组蛋白	储存	冷冻（-20℃）
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产品描述

概述

The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. (The background information is obtained from official databases and does not represent the product information.)

特点

High activity, high purity, low endotoxin, and high batch-to-batch consistency

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Tag	No Tag
Species	Human
Source	E.coli
Uniprot	Q14005
Formulation	Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris, 150 mM NaCl, pH 7.0.
Molecular weight	Approximately 13.4 kDa.
Reconstitution	Before opening the lid, centrifuge to bring the contents to the bottom. Reconstitute with sterile distilled water or PBS and reconstitute to a concentration of 0.1-1.0 mg/ml, which can be further diluted according to subsequent experiments; If stored for a long time, it is recommended to add carrier protein (0.1% BSA) to the dilution buffer; Aliquot is an experimental dosage and cryostored at -80°C to avoid repeated freeze-thaw cycles.
Endotoxin	< 1.0 EU per μg by the LAL method.
AA Sequence	Met1203-Ser1332
Physical Appearance	Lyophilized Powder
Biological Activity	Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CD4+ T Lymphocytes is in a concentration range of 1.0-100 ng/ml.