重组人白介素-19,Recombinant Human Interleukin 19 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C600453

重组人白介素-19

英文名	Recombinant Human Interleukin 19
别名	IL-19; IL19; MDA1; NG.1; ZMDA1; IL-10C
相关类别	重组蛋白	储存	冷冻（-20℃）
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编号	规格	库存	目录价（￥）	您的价格（￥）	数量
C600453-0010	10 UG	咨询	待询价	待询价

产品描述

概述

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. (The background information is obtained from official databases and does not represent the product information.)

特点

High activity, high purity, low endotoxin, and high batch-to-batch consistency

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Tag	No Tag
Species	Human
Source	E.coli
Uniprot	Q9UHD0
Formulation	Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Molecular weight	Approximately 17.9 kDa.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 100 mM HAC to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.
Endotoxin	< 1.0 EU per μg by the LAL method.
AA Sequence	leu25-Ala177
Physical Appearance	Lyophilized Powder
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human IL-20Rα and human IL-20Rβ co-transfected murine BaF3 pro-B cells is less than 1.5 ng/ml, corresponding to a specific activity of > 6.7 × 10^5 IU/mg.