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Order NO. C640020
重组人Galectin-1
英文名 Recombinant Human Galectin-1 (rHuGalectin-1)
别名 Galectin-1, Human
相关类别 其他重组蛋白 储存 冷冻(-20℃)
分子量 Approximately 14.6 kDa, a single non-glycosylated polypeptide chain containing 134 amino acids.    
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C640020-0010 10 UG 预计20日内发货
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产品描述

概述

Human Galectin-1 also named BHL, Galaptin, GBP, L- 14 and LGALS1, is belonging to the galectins family and it is encoded by the LGALS1 gene in human. Galectin-1 is expressed by the endometrial stromal cells throughout the menstrual cycle. Galectin-1 contains a single carbohydrate recognition domain through which it can bind glycans both as a monomer and as a homodimer. Dimers are non-covenantly bound and will spontaneou sly disassociate in low concentration. Galectin -1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin - 1 is thought to play a role in the immunosuppression required for a successful pregnancy. Human Galectin-1 shares 88 %-90 % amino acid sequence identity with rat and mouse.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Physical Appearance Sterile Filtered White lyophilized (freeze- dried) powder.
Purity > 95 % by SDS-PAGE and HPLC analyses.
Source Escherichia coli.
Biological Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human blood monocytes is in a concentration range of 1.0-10 ng/ml.
Formulation Lyophilized from a 0.2 μ m filtered solution in PBS,pH 7.4,with 1 mM DTT.
Endotoxin Less than 0.1 EU/ μg of rHuGalectin -1 as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentrati on of 0.1 - 1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 °C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD
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