小鼠抗CD8单克隆抗体,Anti-CD8 mouse monoclonal antibody 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C650014

小鼠抗CD8单克隆抗体

英文名	Anti-CD8 mouse monoclonal antibody
相关类别	IVD抗体原料最新产品	储存	冷冻（-20℃）参照组件的存储要求

编号	包装	库存	目录价（￥）	您的价格（￥）	数量
C650014-0100	100UG	预计7日内发货
C650014-0500	500UG	预计7日内发货

产品描述

应用

immunohistochemistry：anti-CD8 mouse monoclonal antibody

组分

1 mg/ml

适用样本

Human

属性

Background	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8A gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. CD8B gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Product name	Anti-CD8 mouse monoclonal antibody
Description	Mouse monoclonal antibody to CD8
Host species	Mouse
Tested applications	ELISA, IHC
Reactivity	Human
Immunogen	Synthetic peptide. The exact sequence is proprietary.
Clone number	1F1
Isotype	IgG2a
Purification	Protein A/G affinity column
Uniprot ID	P01732
Background	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8A gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. CD8B gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Product name	Anti-CD8 mouse monoclonal antibody
Description	Mouse monoclonal antibody to CD8
Host species	Mouse
Tested applications	ELISA, IHC
Reactivity	Human
Immunogen	Synthetic peptide. The exact sequence is proprietary.
Clone number	1F1
Isotype	IgG2a
Purification	Protein A/G affinity column
Uniprot ID	P01732
Background	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8A gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. CD8B gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Product name	Anti-CD8 mouse monoclonal antibody
Description	Mouse monoclonal antibody to CD8
Host species	Mouse
Tested applications	ELISA, IHC
Reactivity	Human
Immunogen	Synthetic peptide. The exact sequence is proprietary.
Clone number	1F1
Isotype	IgG2a
Purification	Protein A/G affinity column
Uniprot ID	P01732
Background	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8A gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. CD8B gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Product name	Anti-CD8 mouse monoclonal antibody
Description	Mouse monoclonal antibody to CD8
Host species	Mouse
Tested applications	ELISA, IHC
Reactivity	Human
Immunogen	Synthetic peptide. The exact sequence is proprietary.
Clone number	1F1
Isotype	IgG2a
Purification	Protein A/G affinity column
Uniprot ID	P01732