
Order NO. C650021
小鼠抗CD45单克隆抗体
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
C650021-0100 | 100UG | 预计7日内发货 |
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C650021-0500 | 500UG | 预计7日内发货 |
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产品描述
应用
immunohistochemistry:anti-CD45 mouse monoclonal antibody.human tonsil tissue and vermiform appendix tissue.
组分
1 mg/ml
适用样本
Human
属性
Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. |
Product name | Anti-CD45 mouse monoclonal antibody |
Description | Mouse monoclonal antibody to CD45 |
Host species | Mouse |
Tested applications | IHC |
Reactivity | Human |
Immunogen | Recombinant protein. The exact sequence is proprietary. |
Clone number | SG200376m |
Isotype | IgG2b |
Purification | Protein A/G affinity column |
Uniprot ID | P08575 |