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Order NO. C650030
小鼠抗EMA单克隆抗体
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
C650030-0100 | 100UG | 预计7日内发货 |
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C650030-0500 | 500UG | 预计7日内发货 |
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产品描述
应用
immunohistochemistry:anti-EMA mouse monoclonal antibody.human breast cancer tissue and esophgus cancer tissue.
组分
1 mg/ml
适用样本
Human
属性
Background | This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants. |
Product name | Anti-EMA mouse monoclonal antibody |
Description | Mouse monoclonal antibody to EMA |
Host species | Mouse |
Tested applications | IHC |
Reactivity | Human |
Immunogen | Recombinant protein. The exact sequence is proprietary. |
Clone number | SG200796m |
Isotype | IgG2a |
Purification | Protein A/G affinity column |
Uniprot ID | P15941 |