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Order NO. C650030
小鼠抗EMA单克隆抗体
英文名 Anti-EMA mouse monoclonal antibody
相关类别 IVD抗体原料 最新产品 储存 冷冻(-20℃) 参照组件的存储要求
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C650030-0100 100UG 预计7日内发货
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C650030-0500 500UG 预计7日内发货
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产品描述

应用

immunohistochemistry:anti-EMA mouse monoclonal antibody.human breast cancer tissue and esophgus cancer tissue.

组分

1 mg/ml

适用样本

Human

属性

Background This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
Product name Anti-EMA mouse monoclonal antibody
Description Mouse monoclonal antibody to EMA
Host species Mouse
Tested applications IHC
Reactivity Human
Immunogen Recombinant protein. The exact sequence is proprietary.
Clone number SG200796m
Isotype IgG2a
Purification Protein A/G affinity column
Uniprot ID P15941
相关文档
Sample Application

  • IHC image of EMA staining in a formalin fixed, paraffin embedded human breast cancer tissue (left) and esophgus cancer tissue (right). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer for 20 minutes. The tissue section was then incubated with mouse anti- EMA(C650030)antibody overnight at 4℃.HRP-conjugated goat anti-mouse IgG was used as secondary antibody. (Original magnification: 100×).

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