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Order NO. C650053
小鼠抗WT1单克隆抗体
英文名 | Anti-WT1 mouse monoclonal antibody | ||
相关类别 | IVD抗体原料 | 储存 | 冷冻(-20℃) 参照组件的存储要求 |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
C650053-0100 | 100UG | 预计7日内发货 |
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C650053-0500 | 500UG | 预计7日内发货 |
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产品描述
应用
immunohistochemistry:anti-WT1 mouse monoclonal antibody
组分
1 mg/ml
适用样本
Human
属性
Background | This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. |
Product name | Anti-WT1 mouse monoclonal antibody |
Description | Mouse monoclonal antibody to WT1 |
Host species | Mouse |
Tested applications | IHC |
Reactivity | Human |
Immunogen | Recombinant protein. The exact sequence is proprietary. |
Clone number | SG201706m |
Isotype | IgG2b |
Purification | Protein A/G affinity column |
Uniprot ID | P19544 |