在线客服
网站反馈
网站指南
我的会员中心
中文
我的草稿
我的购物车
Order NO. D111413
癌抗原125（CA125）
英文名 Cancer Antigen 125 (CA125)
别名 mucin 16, cell surface associated; CA125; Cancer Antigen 125; Carbohydrate Antigen; 癌抗原125; 糖链抗原125
相关类别 抗原 储存 冷冻（-20℃）
编 号 规格 库存 目录价（￥） 您的价格（￥） 数 量
D111413-0010 10 KU 预计5日内发货 待询价 待询价
加入购物车
D111413-0050 50 KU 预计5日内发货 待询价 待询价
加入购物车
产品描述

概述

Human Cancer Antigen 125 (CA125)

属性

Full name: mucin 16, cell surface associated
Synonyms: CA125; CA 125; Cancer Antigen 125; Carbohydrate Antigen 125
Swissprot: Q8WXI7
Research areas: Cell Markers, Signal Transduction, Cancer
Background: This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes.
相关文档
质量控制相关文件
质量报告 (COA)
输入LOT号   
查询