Order NO. D111432
P53抗原（重组蛋白）
| 英文名 | P53 Antigen (Recombinant Protein) | ||
| 别名 | tumor protein p53; P53; BCC7; LFS1; BMFS5; TRP53 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D111432-0100 | 100 UG | 预计5日内发货 |
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产品描述
概述
Recombinant protein of human P53
属性
| Full name: | tumor protein p53 |
| Synonyms: | P53; BCC7; LFS1; BMFS5; TRP53 |
| Swissprot: | P04637 |
| Research areas: | Cell Biology, Epigenetics and Nuclear Signaling, Cancer |
| Background: | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). |
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