
Order NO. D111470
人白介素18(IL18)抗原(重组蛋白)
英文名 | Human Interleukin 18 (IL18) Antigen (Recombinant Protein) | ||
别名 | interleukin 18; IGIF; IL-18; IL-1g; IL1F4 | ||
相关类别 | 抗原 | 储存 | 冷冻(-20℃) |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D111470-0100 | 100 UG | 预计5日内发货 |
![]() |
![]() |
![]() |
产品描述
概述
Recombinant protein of human Interleukin 18 (IL18)
属性
Full name: | interleukin 18 |
Synonyms: | IGIF; IL-18; IL-1g; IL1F4 |
Swissprot: | Q14116 |
Expression system: | Escherichia coli |
Research areas: | Immunology, Cancer, Metabolism |
Background: | The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |