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Order NO. D111470
人白介素18(IL18)抗原(重组蛋白)
英文名 Human Interleukin 18 (IL18) Antigen (Recombinant Protein)
别名 interleukin 18; IGIF; IL-18; IL-1g; IL1F4
相关类别 抗原 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D111470-0100 100 UG 预计5日内发货
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产品描述

概述

Recombinant protein of human Interleukin 18 (IL18)

属性

Full name: interleukin 18
Synonyms: IGIF; IL-18; IL-1g; IL1F4
Swissprot: Q14116
Expression system: Escherichia coli
Research areas: Immunology, Cancer, Metabolism
Background: The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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