Order NO. D120008
产品描述
概述
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P14618
|
靶点基因 ID |
5315
|
靶点全称 |
pyruvate kinase M1/2
|
靶点别名 |
PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30
|
靶点研究领域 |
Metabolism, Epigenetics and Nuclear Signaling, Cancer
|
亚型 |
Immunogen-specific rabbit IgG
|