Order NO. D120319
产品描述
概述
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
应用
酶联免疫吸附测定（ELISA），免疫组织化学（IHC）
属性
| 保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
| 运输条件 |
2-8°C
|
| 靶点 Uniprot 登记号 |
P36894
|
| 靶点基因 ID |
657
|
| 靶点全称 |
bone morphogenetic protein receptor type 1A
|
| 靶点别名 |
ALK3; SKR5; ALK-3; CD292; ACVRLK3; BMPR-1A; 10q23del
|
| 靶点研究领域 |
Signal Transduction, Stem Cells, Cardiovascular, Metabolism
|
| 亚型 |
Immunogen-specific rabbit IgG
|
