Order NO. D120402
产品描述
概述
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB）
属性
| 保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
| 运输条件 |
2-8°C
|
| 靶点 Uniprot 登记号 |
P50750
|
| 靶点基因 ID |
1025
|
| 靶点全称 |
cyclin-dependent kinase 9
|
| 靶点别名 |
TAK, C-2k, CTK1, CDC2L4, PITALRE
|
| 靶点研究领域 |
Epigenetics and Nuclear Signaling, Cancer, Immunology
|
| 亚型 |
Immunogen-specific rabbit IgG
|
