Order NO. D120606
兔抗DUSP6多克隆抗体
| 英文名 | Anti-DUSP6 rabbit polyclonal antibody | ||
| 别名 | MKP3, PYST1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
| 抗原 | DUSP6 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D120606-0025 | 25 ul | 现货 |
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| D120606-0100 | 100 ul | 现货 |
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| D120606-0200 | 200 ul | 现货 |
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属性
| Background: | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014] (The background information is obtained from official databases and does not represent the product information.) |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | DUSP6 |
| Immunogen: | Recombinant protein of human DUSP6 |
| Full name: | dual specificity phosphatase 6 |
| Synonyms: | HH19; MKP3; PYST1 |
| SwissProt: | Q16828 |
| ELISA Recommended dilution: | 1000-5000 |
| IHC positive control: | Human ovarian cancer and Human tonsil |
| IHC Recommend dilution: | 25-100 |
| WB Predicted band size: | 42 kDa |
| WB Positive control: | Mouse heart tissue lysate |
| WB Recommended dilution: | 1000-5000 |
相关文档
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Sample Application
