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Order NO. D120874
兔抗IRF4多克隆抗体
英文名 Anti-IRF4 rabbit polyclonal antibody
别名 MUM1; LSIRF; SHEP8; NF-EM5
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 IRF4
编 号 规格 库存 目录价(¥) 您的价格(¥) 数 量
D120874-0025 25 ul 现货 500 500
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D120874-0100 100 ul 现货 1600 1600
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D120874-0200 200 ul 现货 2500 2500
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产品描述

概述

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q15306
靶点基因 ID 3662
靶点全称 interferon regulatory factor 4
靶点别名 MUM1; LSIRF; SHEP8; NF-EM5
靶点研究领域 Epigenetics and Nuclear Signaling, Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using D120874(IRF4 Antibody) at dilution 1/40. (Original magnification: ×200)