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Order NO. D121064
兔抗OAS2多克隆抗体
英文名 Anti-OAS2 rabbit polyclonal antibody
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 OAS2
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D121064-0025 25 ul 现货
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D121064-0100 100 ul 现货
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D121064-0200 200 ul 现货
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产品描述

概述

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P29728
靶点基因 ID 4939
靶点全称 2'-5'-oligoadenylate synthetase 2
靶点研究领域 Epigenetics and Nuclear Signaling, Immunology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D121064(OAS2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D121064(OAS2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)


  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: A375, RAW264.7, MC3T3-E1 cell lysates, Primary antibody: D121064(OAS2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 3 minutes
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