Order NO. D121182
产品描述
概述
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P41222
|
靶点基因 ID |
5730
|
靶点全称 |
prostaglandin D2 synthase
|
靶点别名 |
PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS
|
靶点研究领域 |
Signal Transduction
|
亚型 |
Immunogen-specific rabbit IgG
|