Order NO. D121371
产品描述
概述
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q16620
|
靶点基因 ID |
4915
|
靶点全称 |
neurotrophic receptor tyrosine kinase 2
|
靶点别名 |
TRKB; trk-B; GP145-TrkB
|
靶点研究领域 |
Cancer, Metabolism, Neuroscience
|
亚型 |
Immunogen-specific rabbit IgG
|