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编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D121501-0025 | 25 ul | 现货 |
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D121501-0100 | 100 ul | 现货 |
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D121501-0200 | 200 ul | 现货 |
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概述
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | Q13444 |
靶点基因 ID | 8751 |
靶点全称 | ADAM metallopeptidase domain 15 |
靶点别名 | MDC15 |
靶点研究领域 | Signal Transduction, Cell Biology |
亚型 | Immunogen-specific rabbit IgG |