Order NO. D121614
兔抗PRKAA2多克隆抗体
| 英文名 | Anti-PRKAA2 rabbit polyclonal antibody | ||
| 别名 | AMPK; AMPK2; PRKAA; AMPKa2 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
| 抗原 | PRKAA2 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D121614-0025 | 25 ul | 现货 |
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| D121614-0100 | 100 ul | 现货 |
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| D121614-0200 | 200 ul | 现货 |
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属性
| Background: | The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. (The background information is obtained from official databases and does not represent the product information.) |
| Applications: | ELISA, IHC |
| Name of antibody: | PRKAA2 |
| Immunogen: | Fusion protein of human PRKAA2 |
| Full name: | protein kinase AMP-activated catalytic subunit alpha 2 |
| Synonyms: | AMPK; AMPK2; PRKAA; AMPKa2 |
| SwissProt: | P54646 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human thyroid cancer and Human bladder cancer |
| IHC Recommend dilution: | 50-200 |
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Sample Application
