Order NO. D122181
产品描述
概述
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q02318
|
靶点基因 ID |
1593
|
靶点全称 |
cytochrome P450, family 27, subfamily A, polypeptide 1
|
靶点别名 |
CTX; CP27; CYP27
|
靶点研究领域 |
Metabolism, Cancer, Cardiovascular
|
亚型 |
Immunogen-specific rabbit IgG
|