Order NO. D122232
兔抗DHCR7多克隆抗体
| 英文名 | Anti-DHCR7 rabbit polyclonal antibody | ||
| 别名 | SLOS | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse |
| 标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
| 抗原 | DHCR7 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D122232-0025 | 25 ul | 现货 |
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| D122232-0100 | 100 ul | 现货 |
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| D122232-0200 | 200 ul | 现货 |
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属性
| Background: | This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by cognitive disability, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Aug 2009] (The background information is obtained from official databases and does not represent the product information.) |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | DHCR7 |
| Immunogen: | Recombinant protein of human DHCR7 |
| Full name: | 7-dehydrocholesterol reductase |
| Synonyms: | SLOS |
| SwissProt: | Q9UBM7 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human liver cancer and Human gastric cancer |
| IHC Recommend dilution: | 50-200 |
| WB Predicted band size: | 54 kDa |
| WB Positive control: | Caco-2, MCF7, Hela, LO2 cell, Mouse brain tissue lysates |
| WB Recommended dilution: | 1000-5000 |
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