Order NO. D122346
产品描述
概述
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q12884
|
靶点基因 ID |
2191
|
靶点全称 |
fibroblast activation protein alpha
|
靶点别名 |
FAPA; SIMP; DPPIV; FAPalpha
|
靶点研究领域 |
Signal Transduction, Cancer, Cell Biology
|
亚型 |
Immunogen-specific rabbit IgG
|