Order NO. D122384
产品描述
概述
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q06787
|
靶点基因 ID |
2332
|
靶点全称 |
fragile X mental retardation 1
|
靶点别名 |
POF; FMRP; POF1; FRAXA
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Neuroscience
|
亚型 |
Immunogen-specific rabbit IgG
|