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Order NO. D122399
兔抗GADD45B多克隆抗体
英文名 Anti-GADD45B rabbit polyclonal antibody
别名 MYD118; GADD45BETA
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 GADD45B
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D122399-0025 25 ul 现货
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D122399-0100 100 ul 现货
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D122399-0200 200 ul 现货
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产品描述

概述

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 O75293
靶点基因 ID 4616
靶点全称 growth arrest and DNA-damage-inducible, beta
靶点别名 MYD118; GADD45BETA
靶点研究领域 Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Immunology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using D122399(GADD45B Antibody) at dilution 1/30. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human brain tissue using D122399(GADD45B Antibody) at dilution 1/30. (Original magnification: ×200)
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