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Order NO. D122499
兔抗HSD11B1多克隆抗体
英文名 Anti-HSD11B1 rabbit polyclonal antibody
别名 hydroxysteroid 11-beta dehydrogenase 1; HDL; 11-DH; HSD11; HSD11B; HSD11L; CORTRD2; SDR26C1; 11-beta-HSD1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 HSD11B1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D122499-0025 25 ul 现货
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D122499-0100 100 ul 现货
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D122499-0200 200 ul 现货
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产品描述

概述

The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P28845
靶点基因 ID 3290
靶点全称 hydroxysteroid 11-beta dehydrogenase 1
靶点别名 HDL; 11-DH; HSD11; HSD11B; HSD11L; CORTRD2; SDR26C1; 11-beta-HSD1
靶点研究领域 Metabolism, Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using D122499(HSD11B1 Antibody) at dilution 1/70, on the right is treated with fusion protein. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D122499(HSD11B1 Antibody) at dilution 1/70, on the right is treated with fusion protein. (Original magnification: ×200)

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