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| 编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
| D122520-0025 | 25 ul | 现货 | 待询价 | 待询价 | |
| D122520-0100 | 100 ul | 现货 | 待询价 | 待询价 | |
| D122520-0200 | 200 ul | 现货 | 待询价 | 待询价 |
概述
This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q12891 |
| 靶点基因 ID | 8692 |
| 靶点全称 | hyaluronoglucosaminidase 2 |
| 靶点别名 | LUCA2 |
| 靶点研究领域 | Signal Transduction |
| 亚型 | Immunogen-specific rabbit IgG |
