Order NO. D123094
产品描述
概述
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q12770
|
靶点基因 ID |
22937
|
靶点全称 |
SREBF chaperone
|
靶点研究领域 |
Metabolism, Signal Transduction, Cardiovascular
|
亚型 |
Immunogen-specific rabbit IgG
|