Order NO. D123097
产品描述
概述
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P35354
|
靶点基因 ID |
5743
|
靶点全称 |
prostaglandin-endoperoxide synthase 2
|
靶点别名 |
COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
|
靶点研究领域 |
Signal Transduction, Cancer, Metabolism, Cardiovascular
|
亚型 |
Immunogen-specific rabbit IgG
|