Order NO. D123228
产品描述
概述
RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation (PubMed:18056422). Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammaotry cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes (PubMed:26382853). May play roles in cilia formation and/or maintenance.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P10155
|
靶点基因 ID |
6738
|
靶点全称 |
Ro60, Y RNA binding protein
|
靶点别名 |
SSA2; RORNP; TROVE2
|
靶点研究领域 |
Immunology, Epigenetics and Nuclear Signaling
|
亚型 |
Immunogen-specific rabbit IgG
|