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编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D123689-0025 | 25 ul | 现货 | 待询价 | 待询价 |
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D123689-0100 | 100 ul | 现货 | 待询价 | 待询价 |
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D123689-0200 | 200 ul | 现货 | 待询价 | 待询价 |
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概述
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF621 (Zinc finger protein 621) is a 439 amino acid nuclear protein that contains one KRAB domain and seven C2H2-type zinc fingers. The gene encoding ZNF621 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. There are two isoforms of ZNF621 that are produced as a result of alternative splicing events. May be involved in transcriptional regulation.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | Q6ZSS3 |
靶点基因 ID | 285268 |
靶点全称 | zinc finger protein 621 |
靶点研究领域 | Epigenetics and Nuclear Signaling |
亚型 | Immunogen-specific rabbit IgG |

