Order NO. D123901
产品描述
概述
May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q9GZX9
|
靶点基因 ID |
57045
|
靶点全称 |
twisted gastrulation BMP signaling modulator 1
|
靶点别名 |
TSG
|
靶点研究领域 |
Neuroscience
|
亚型 |
Immunogen-specific rabbit IgG
|