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Order NO. D124486
兔抗CDC45多克隆抗体
英文名 Anti-CDC45 rabbit polyclonal antibody
别名 cell division cycle 45; CDC45L; CDC45L2; PORC-PI-1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 CDC45
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D124486-0025 25 ul 现货
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D124486-0100 100 ul 现货
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D124486-0200 200 ul 现货
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产品描述

概述

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 O75419
靶点基因 ID 8318
靶点全称 cell division cycle 45
靶点别名 CDC45L; MGORS7; CDC45L2; PORC-PI-1
靶点研究领域 Epigenetics and Nuclear Signaling, Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using D124486(CDC45 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)

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