精确搜索
我的草稿
我的购物车
精确搜索
询价单号 点击跳转查看 X
| 编 号 | 规格 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D125034-0025 | 25 ul | 现货 | 待询价 | 待询价 | |
| D125034-0100 | 100 ul | 现货 | 待询价 | 待询价 | |
| D125034-0200 | 200 ul | 现货 | 待询价 | 待询价 |
概述
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | P01127 |
| 靶点基因 ID | 5155 |
| 靶点全称 | platelet derived growth factor subunit B |
| 靶点别名 | SIS; SSV; IBGC5; PDGF2; c-sis; PDGF-2 |
| 靶点研究领域 | Signal Transduction, Cancer, Cardiovascular, Metabolism, Developmental Biology |
| 亚型 | Immunogen-specific rabbit IgG |
结算方信息确认
申请授权
请填写负责人信息
