Order NO. D125163
产品描述
概述
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P08237
|
靶点基因 ID |
5213
|
靶点全称 |
phosphofructokinase, muscle
|
靶点别名 |
GSD7; PFK1; PFKA; PFKX; PFK-1; ATP-PFK; PPP1R122
|
靶点研究领域 |
Metabolism, Cancer
|
亚型 |
Immunogen-specific rabbit IgG
|