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Order NO. D125189
兔抗C9orf116多克隆抗体
英文名 Anti-C9orf116 rabbit polyclonal antibody
别名 chromosome 9 open reading frame 116; PIERCE1; RbEST47
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 C9orf116
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D125189-0025 25 ul 现货
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D125189-0100 100 ul 现货
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D125189-0200 200 ul 现货
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产品描述

概述

C9orf116, also known as PIERCE1. PIERCE1 is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q5BN46
靶点基因 ID 138162
靶点全称 chromosome 9 open reading frame 116
靶点别名 PIERCE1; RbEST47
靶点研究领域 Cell Biology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using D125189(C9orf116 Antibody) at dilution 1/40. (Original magnification: ×200)
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