Order NO. D125243
兔抗RNF111多克隆抗体
| 英文名 | Anti-RNF111 rabbit polyclonal antibody | ||
| 别名 | ring finger protein 111; ARK; hRNF111 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse |
| 克隆类型 | rabbit polyclonal | 抗原 | RNF111 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D125243-0025 | 25 ul | 现货 |
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| D125243-0100 | 100 ul | 现货 |
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| D125243-0200 | 200 ul | 现货 |
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产品描述
概述
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q6ZNA4 |
| 靶点基因 ID | 54778 |
| 靶点全称 | ring finger protein 111 |
| 靶点别名 | ARK; hRNF111 |
| 靶点研究领域 | Cell Biology |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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Sample Application
