Order NO. D125310
产品描述
概述
The small GTPases Rab are key regulators in vesicle trafficking (PubMed:24788816). Essential for maintaining the integrity of the endosome-trans-Golgi network structure (By similarity). Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner (PubMed:24788816). Recruits LRRK2 to the Golgi complex and stimulates LRRK2 kinase activity (PubMed:29212815). Regulates neuronal process morphology in the intact central nervous system (CNS) (By similarity). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection (PubMed:22042847).
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
| 运输条件 |
2-8°C
|
| 靶点 Uniprot 登记号 |
O14966
|
| 靶点基因 ID |
8934
|
| 靶点全称 |
RAB29, member RAS oncogene family
|
| 靶点别名 |
RAB7L; RAB7L1
|
| 靶点研究领域 |
Signal Transduction
|
| 亚型 |
Immunogen-specific rabbit IgG
|
