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Order NO. D125873
兔抗IFT57多克隆抗体
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D125873-0025 | 25 ul | 现货 |
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| D125873-0100 | 100 ul | 现货 |
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| D125873-0200 | 200 ul | 现货 |
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产品描述
概述
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
应用
酶联免疫吸附测定（ELISA），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q9NWB7 |
| 靶点基因 ID | 55081 |
| 靶点全称 | intraflagellar transport 57 |
| 靶点别名 | HIPPI; MHS4R2; ESRRBL1 |
| 靶点研究领域 | Neuroscience |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
Sample Application
