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Order NO. D145022
人TNFRSF18重组蛋白(mFc-6×His tag C-Terminus)
英文名 Human TNFRSF18 Recombinant protein (mFc-6×His tag C-Terminus)
别名 TNF receptor superfamily member 18; AITR; GITR; CD357; GITR-D; ENERGEN
相关类别 抗原 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D145022-0010 10 UG 预计30日内发货
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D145022-0050 50 UG 预计30日内发货
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D145022-0100 100 UG 预计30日内发货
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产品描述

概述

Fusion protein corresponding to a region derived from 26-162 amino acids of Human TNFRSF18

属性

Full name: TNF receptor superfamily member 18
Synonyms: AITR; GITR; CD357; GITR-D; ENERGEN
Swissprot: Q9Y5U5
Purity: >95%, as determined by Coomassie blue stained SDS-PAGE
Expression system: HEK293
Tags: mFc-6×His tag C-Terminus
Species: Human
Molecular mass: The protein has a predicted molecular weight of 50-52 kDa after removal of the signal peptide.
Research areas: Immunology, Signal Transduction, Cancer
Background: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
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Sample Application

  • HEK293 cell line transfected with irrelevant protein (B) and human TNFSF18 (A) were surface stained with Human TNFRSF18, mFc-His tagged protein (Catalog number: D145022) 1 μg/ml followed by Alexa 488-conjugated anti-mouse IgG secondary antibody.

  • Purified Human TNFRSF18 Recombinant Protein (Catalog number: D145022) was analyzed by SDS-PAGE gel and Coomossie Blue Staining.
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