Order NO. D145089
人CD46重组蛋白（6×His tag C-Terminus）
| 英文名 | Human CD46 Recombinant protein (6×His tag C-Terminus) | ||
| 别名 | CD46 molecule; MCP; TLX; AHUS2; MIC10; TRA2.10 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D145089-0010 | 10 UG | 预计5日内发货 |
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| D145089-0050 | 50 UG | 预计5日内发货 |
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| D145089-0100 | 100 UG | 预计5日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 35-328 amino acids of Human CD46
属性
| Full name: | CD46 molecule |
| Synonyms: | MCP; TLX; AHUS2; MIC10; TRA2.10 |
| Swissprot: | P15529 |
| Purity: | >95%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | HEK293 |
| Tags: | 6×His tag C-Terminus |
| Species: | Human |
| Molecular mass: | The protein has a predicted molecular weight of 33.5 kDa after removal of the signal peptide. The apparent molecular weight of CD46-His is approximately 55-70 kDa due to glycosylation. |
| Research areas: | Immunology |
| Background: | The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010] |
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