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Order NO. D145146
人CD86重组蛋白(hFc tag C-Terminus)
英文名 Human CD86 Recombinant protein (hFc tag C-Terminus)
别名 CD86 molecule; B70; B7-2; B7.2; LAB72; CD28LG2
相关类别 抗原 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D145146-0010 10 UG 预计5日内发货
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D145146-0050 50 UG 预计5日内发货
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D145146-0100 100 UG 预计5日内发货
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产品描述

概述

Fusion protein corresponding to a region derived from 26-247 amino acids of Human CD86

属性

Full name: CD86 molecule
Synonyms: B70; B7-2; B7.2; LAB72; CD28LG2
Swissprot: P42081
Purity: >95%, as determined by Coomassie blue stained SDS-PAGE
Expression system: HEK293
Tags: hFc tag C-Terminus
Species: Human
Molecular mass: The protein has a predicted molecular weight of 51.5 kDa after removal of the signal peptide.
Research areas: Immunology, Stem Cells
Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
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Sample Application

  • ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CD86, hFc tagged protein (Catalog number: D145146) can bind Human CTLA4, mFc-His tagged protein (Catalog number: D145020) in a linear range of 0.048-2.694 ng/ml.

  • HEK293 cell line transfected with irrelevant protein (B) and human CD28 (A) were surface stained with Human CD86, hFc tagged protein (Catalog number: D145146) 1 μg/ml followed by Alexa 488-conjugated anti-human IgG secondary antibody.

  • Purified Human CD86 Recombinant Protein (Catalog number: D145146) was analyzed by SDS-PAGE gel and Coomossie Blue Staining.
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