Order NO. D145184
人IL6R重组蛋白（hFc tag C-Terminus）
| 英文名 | Human IL6R Recombinant protein (hFc tag C-Terminus) | ||
| 别名 | interleukin 6 receptor; IL6Q; gp80; CD126; HIES5; IL-6R; IL6RA; IL6RQ; IL-1Ra; IL-6RA; IL6QTL; IL-6R-1 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D145184-0010 | 10 UG | 预计5日内发货 |
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| D145184-0050 | 50 UG | 预计5日内发货 |
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| D145184-0100 | 100 UG | 预计5日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 20-365 amino acids of Human IL6R
属性
| Full name: | interleukin 6 receptor |
| Synonyms: | IL6Q; gp80; CD126; HIES5; IL-6R; IL6RA; IL6RQ; IL-1Ra; IL-6RA; IL6QTL; IL-6R-1 |
| Swissprot: | P08887 |
| Purity: | >95%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | HEK293 |
| Tags: | hFc tag C-Terminus |
| Species: | Human |
| Molecular mass: | The protein has a predicted molecular weight of 64.7 kDa after removal of the signal peptide. The apparent molecular weight of IL6R-hFc is approximately 70-100 kDa due to glycosylation. |
| Research areas: | Immunology, Stem Cells |
| Background: | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020] |
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