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Order NO. D145190
人STING1重组蛋白(hFc tag N-Terminus)
编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D145190-0010 | 10 UG | 预计5日内发货 | 待询价 | 待询价 |
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D145190-0050 | 50 UG | 预计5日内发货 | 待询价 | 待询价 |
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D145190-0100 | 100 UG | 预计5日内发货 | 待询价 | 待询价 |
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产品描述
概述
Fusion protein corresponding to a region derived from 139-379 amino acids of Human STING1
属性
Full name: | stimulator of interferon response cGAMP interactor 1 |
Synonyms: | ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta |
Swissprot: | Q86WV6 |
Purity: | >90%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | HEK293 |
Tags: | hFc tag N-Terminus |
Species: | Human |
Molecular mass: | The protein has a predicted molecular weight of 53.2 kDa after removal of the signal peptide. |
Research areas: | Immunology, Signal Transduction, Epigenetics and Nuclear Signaling |
Background: | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
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