Order NO. D145205
人IL18重组蛋白（hFc tag C-Terminus）
| 英文名 | Human IL18 Recombinant protein (hFc tag C-Terminus) | ||
| 别名 | interleukin 18; IGIF; IL-18; IL-1g; IL1F4 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D145205-0010 | 10 UG | 预计5日内发货 |
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| D145205-0050 | 50 UG | 预计5日内发货 |
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| D145205-0100 | 100 UG | 预计5日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 37-197 amino acids of Human IL18
属性
| Full name: | interleukin 18 |
| Synonyms: | IGIF; IL-18; IL-1g; IL1F4 |
| Swissprot: | Q14116 |
| Purity: | >95%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | HEK293 |
| Tags: | hFc tag C-Terminus |
| Species: | Human |
| Molecular mass: | The protein has a predicted molecular weight of 44.3 kDa after removal of the signal peptide. The apparent molecular weight of IL18-mFc is approximately 35-55 kDa due to glycosylation. |
| Research areas: | Immunology, Cancer, Metabolism |
| Background: | The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020] |
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