Order NO. D145238
人CD68重组蛋白（6×His tag C-Terminus）
| 英文名 | Human CD68 Recombinant protein (6×His tag C-Terminus) | ||
| 别名 | CD68 molecule; GP110; LAMP4; SCARD1 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D145238-0010 | 10 UG | 预计5日内发货 |
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| D145238-0050 | 50 UG | 预计5日内发货 |
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| D145238-0100 | 100 UG | 预计5日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 22-319 amino acids of Human CD68
属性
| Full name: | CD68 molecule |
| Synonyms: | GP110; LAMP4; SCARD1 |
| Swissprot: | P34810 |
| Purity: | >95%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | HEK293 |
| Tags: | 6×His tag C-Terminus |
| Species: | Human |
| Molecular mass: | The protein has a predicted molecular weight of 32.4 kDa after removal of the signal peptide. The apparent molecular weight of CD68-His is approximately 55-130 kDa due to glycosylation. |
| Research areas: | Immunology |
| Background: | This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008] |
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