Order NO. D145279
人CD74重组蛋白（hFc tag N-Terminus）
| 英文名 | Human CD74 Recombinant protein (hFc tag N-Terminus) | ||
| 别名 | CD74 molecule; II; p33; CLIP; DHLAG; HLADG; Ia-GAMMA | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D145279-0050 | 50 UG | 预计5日内发货 |
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| D145279-0100 | 100 UG | 预计5日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 73-296 amino acids of Human CD74
属性
| Full name: | CD74 molecule |
| Synonyms: | II; p33; CLIP; DHLAG; HLADG; Ia-GAMMA |
| Swissprot: | P04233 |
| Purity: | >95%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | HEK293 |
| Tags: | hFc tag N-Terminus |
| Species: | Human |
| Molecular mass: | The protein has a predicted molecular weight of 51.5 kDa after removal of the signal peptide. The apparent molecular weight of hFc-CD74 is approximately 55-70 kDa due to glycosylation. |
| Research areas: | Immunology, Microbiology |
| Background: | The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
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