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Order NO. D145360
人IL31重组蛋白(hFc tag C-Terminus)
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D145360-0010 | 10 UG | 预计5日内发货 |
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D145360-0050 | 50 UG | 预计5日内发货 |
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D145360-0100 | 100 UG | 预计5日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 24-164 amino acids of Human IL31
属性
Full name: | interleukin 31 |
Synonyms: | IL-31 |
Swissprot: | Q6EBC2 |
Purity: | >95%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | HEK293 |
Tags: | hFc tag C-Terminus |
Species: | Human |
Molecular mass: | The protein has a predicted molecular weight of 42 kDa after removal of the signal peptide. The apparent molecular weight of IL31-hFc is approximately 35-55 kDa due to glycosylation. |
Research areas: | Immunology |
Background: | IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]). |