Order NO. D145580
小鼠Cd86重组蛋白(hFc tag C-Terminus)
英文名 | Mouse Cd86 Recombinant protein (hFc tag C-Terminus) | ||
别名 | CD86 antigen; B7; B70; MB7; B7-2; B7.2; CLS1; Ly58; ETC-1; Ly-58; MB7-2; Cd28l2; TS/A-2 | ||
相关类别 | 抗原 | 储存 | 冷冻(-20℃) |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D145580-0010 | 10 UG | 预计5日内发货 |
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D145580-0050 | 50 UG | 预计5日内发货 |
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D145580-0100 | 100 UG | 预计5日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 24-245 amino acids of Mouse Cd86
属性
Full name: | CD86 antigen |
Synonyms: | B7; B70; MB7; B7-2; B7.2; CLS1; Ly58; ETC-1; Ly-58; MB7-2; Cd28l2; TS/A-2 |
Swissprot: | P42082 |
Purity: | >95%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | HEK293 |
Tags: | hFc tag C-Terminus |
Species: | Mouse |
Molecular mass: | The protein has a predicted molecular weight of 51.4 kDa after removal of the signal peptide. The apparent molecular weight of Mouse Cd86-hFc is approximately 55-70 kDa due to glycosylation. |
Research areas: | Immunology, Stem Cells |
Background: | Predicted to enable signaling receptor binding activity. Involved in several processes, including CD40 signaling pathway; activation of phospholipase C activity; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; defense response to virus; and positive regulation of T cell proliferation. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Is expressed in central nervous system and retina. Used to study Guillain-Barre syndrome. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; autoimmune disease (multiple); chronic lymphocytic leukemia; chronic obstructive pulmonary disease; and systemic scleroderma. Orthologous to human CD86 (CD86 molecule). |