Order NO. D145669
人KLK3重组蛋白（6×His tag C-Terminus）
| 英文名 | Human KLK3 Recombinant protein (6×His tag C-Terminus) | ||
| 别名 | kallikrein related peptidase 3; APS; PSA; hK3; KLK2A1 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D145669-0010 | 10 UG | 预计5日内发货 |
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| D145669-0050 | 50 UG | 预计5日内发货 |
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| D145669-0100 | 100 UG | 预计5日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 18-261 amino acids of Human KLK3
属性
| Full name: | kallikrein related peptidase 3 |
| Synonyms: | APS; PSA; hK3; KLK2A1 |
| Swissprot: | P07288 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | HEK293 |
| Tags: | 6×His tag C-Terminus |
| Species: | Human |
| Molecular mass: | The protein has a predicted molecular weight of 27.7 kDa after removal of the signal peptide. The apparent molecular weight of KLK3-His is approximately 25-35 kDa due to glycosylation. |
| Research areas: | Signal Transduction, Cancer, Neuroscience |
| Background: | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. |
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